ROTENOIDS & RELATED O-HETEROCYCLES
The rotenoids are a group of closely related, multi-ring O-heterocycles linked biosynthetically, but also by their insecticidal properties. This latter property has encouraged their use, notably rotenone itself, as natural pesticides. In recent literature, the rotenoids have been reported to have a much wider scope of activity in mamallian systems that suggests both therapeutic and toxicological indications. Rotenone, which is readily available, has been studied extensively, however, less common members, such as deguelin, have been shown to have striking effects in antineoplastic and related areas.
GAIA provides access to many rotenoids for both research and product development.
R2000: HAEMATOXYLIN
R2200: BRAZILIN
R3000: (-)DEGUELIN
CAS #: 522-17-8; C23H22O6; mol wt: 394.42
Occurrence: Derris, Lonchocarpus, Millettia and Tephrosia spp
pale yellow glass (racemate is crystalline, mp 171°); [a]D -101 (C6H6)
JACS 54:3000(1932); 56:2415(1934)Availability: 100 mg, 1 gram
Purity: 95% by HPLC
R3700: HOMOPTEROCARPIN
R3800: MUNDULONE
R3870: DIHYDROMUNDULETONE
R4000: (-)ROTENONE
CAS #: 83-79-4; C23H22O6; mol wt: 394.42
Occurrence: Derris & Lonchocarpus spp, and numerous other Fabaceae
colorless crystals, mp 160-161°C; [a]D -225 (C6H6).
Chem Rev 12: 181 (1933)Availability: 1 gram, 10 gram
Purity: 98% by TLC
R4100: ROTENONE, DEHYDRO-
R4200: ROTENONE, DIHYDRO-
R4500: (-)ISOROTENONE
C23H22O6; mol wt: 394.42
Occurrence: derivative of rotenone
colorless crystals, mp 184-185°C; Chem Rev 12: 181 (1933)Availability: 100 mg, 1 gram
Purity: 98% by TLCR4550: ROTENONIC ACID
R5000:OSAJIN
R5500:POMIFERIN
R7000:PACHYRRHIZIN
R7100:PACHYRRHIZONE
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